Advances in the catalytic, asymmetric synthesis of beta-lactams.
نویسندگان
چکیده
In this Account, we illustrate our contribution to the catalytic, asymmetric synthesis of beta-lactams through a flexible [2 + 2] cycloaddition strategy. We also explore the scope of our methodology and comment on future directions.
منابع مشابه
Column asymmetric catalysis for beta-lactam synthesis.
[structure] A catalytic asymmetric reaction process was designed involving the use of solid-phase reagents and catalysts that constitute the packing of a series of "reaction columns". This process was applied to the catalytic asymmetric synthesis of beta-lactams, yielding pure product after crystallization with exceptional enantio- and diastereoselectivity.
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عنوان ژورنال:
- Accounts of chemical research
دوره 37 8 شماره
صفحات -
تاریخ انتشار 2004